One Molecule at a Time.
HydroSepREE is commercializing a patented, water-based chemistry platform that selectively separates heavy rare earth elements — solving the critical bottleneck no Western company has cracked at scale.
A chemistry breakthrough purpose-built for the world's most neglected critical mineral bottleneck.
Supramolecular cyclen-based macrocyclic molecular recognition — a wholly new approach to REE selectivity.
Near-neutral pH selective precipitation replaces solvent extraction — no toxic organics, dramatically simpler plant design.
Directly solves the Dy/Tb/Ho bottleneck — the hardest separations in inorganic chemistry, 2–5× harder than light REEs.
99%–99.5% oxides today with a clear pathway to 99.7% — meeting next-generation permanent magnet specifications.
Context: EVs, wind, robotics, defense, and AI infrastructure amplify demand, while US/EU policies accelerate domestic mandates — yet no scalable Western heavy-REE separation facilities exist today.
Separation is where purity, margin, and control reside. Separation defines oxide purity; oxide purity defines magnet performance (OEM-grade requires ~99–99.9% purity). Separation, not mining, is the structural bottleneck.
Three interlocking innovations in aqueous chemistry that solve what solvent extraction cannot.
Cyclen-type macrocyclic chelators act as size-selective recognition platforms — engineered to distinguish lanthanides by ionic radius at the picometer scale.
Pendant arms amplify ionic-radius differences into sharp solubility transitions — converting near-identical chemistry into separable fractions.
Selective precipitation at near-neutral pH — no organic solvents required. Dramatically lower CAPEX, OPEX, and environmental footprint vs. incumbent SX.
Peer-reviewed data demonstrating selectivity, throughput, chelator stability, and closed-loop recycle performance.
Achieved for Dy/Tb/Ho — the hardest separations in the entire lanthanide series, where incumbent SX struggles most.
Current results already hit OEM-grade targets. Clear roadmap to 99.9%+ (defense grade) through iterative chelator engineering.
Proven selectivity, throughput, chelator stability, and closed-loop recycle cycles — all key pre-pilot milestones achieved.
HydroSepREE sits at the intersection of primary mining, recycling, and defense supply chain mandates.
Two co-founders with complementary and highly relevant expertise at the commercial and scientific intersection.
20+ years scaling deep tech ventures. Raised $100M+ in capital. Led multiple companies to successful IPO, RTO, and M&A exits. Expert in bridging science to commercial markets at scale.
20+ years of R&D in rare-earth chemistry. Core IP inventor. Previously developed the Lu-177 separation technology now deployed industrially by SHINE Technologies — proving the path from lab to industrial scale.
1,000+ employees within the Czech Academy of Sciences. Global research leader in organic chemistry, biochemistry, and molecular sciences. Unmatched commercialization track record, including Prof. Antonín Holý's antiviral discoveries successfully licensed to Gilead Sciences.
HydroSepREE is seeking strategic investment partners to accelerate scale-up from validated lab results to pilot plant. We're offering early-stage terms to aligned investors who understand the critical minerals opportunity.